Combinations of fixed-dose drugs may be a reasonable option for some patients previously treated but not recommended as initial choice (9). In 10-20% of the patients either by the severity of your hypertension or by interference that reduce the effectiveness of treatment is necessary to use three or more drugs. The multiple combinations often include a diuretic because, when they have ruled out other causes of refractoriness, one of the most common reasons for the lack of adequate response is an excessive intake of salt in the diet (17) 8 .- INTERVALS WHICH TIME IS OF THE AGENTS added or replace? Increasing the dose of a drug, the addition or replacement will be in 1 or 2 months except in cases of severe hypertension in which the periods must be stated at the evolution (9) 9 .- What METHOD OF MONITORING HYPERTENSIVE PERFORM? The main objective is to verify that the PA is kept in optimal control figures. If you would like to know more about supermodel, then click here. The hypertensive phase I or II of the JNC VI with good blood pressure control may be reassessed every 3-6 months for nursing and once a year by the doctor to check adherence and tolerance to treatment, noted the practice of healthy habits, make an interrogation addressed to the target organ involvement and perform a complete physical examination. In patients without cardiovascular complications or other diseases associated with FR or yearly analytical is advised creatinine, glucose, cholesterol, triglycerides, uric acid, sodium and potassium. The electrolytes will be optional after a month of starting treatment with diuretics, ACE inhibitors or ARBs. For even more analysis, hear from Cindy Crawford.